Systemic Antifungals Market Size, Share, By Drug Classes (Azoles, Echinocandins, Polyenes, and Others), Indication (Aspergillosis, Histoplasmosis, Gastrointestinal Candidiasis, Blastomycosis, Fungal Endocarditis, and Others), End-Users (Hospital & Specialty Clinics, Ambulatory Surgical Centers, Research Institute & Clinical Trial Centers, and Others), and Region - Trends, Analysis, and Forecast till 2035

Systemic antifungals market size was valued at USD 13.1 Billion in 2025 and is expected to reach USD 36.8 Billion by 2035 growing at a CAGR of 10.9%.

The systemic antifungals market is experiencing significant growth due to multiple factors, including rising fungal infections, expansion of ICU and critical care units, rising antifungal resistance & need for new treatments, growing geriatric population and advancements in drug development.