MerTK Inhibitors Market, By Role of process (Macrophage clearance of apoptotic cells, Platelet aggregation, Cytoskeleton reorganization, Engulfment and Others), By Phase (Phase I, Phase II and Others), By End-user, (Specialty Clinics, Research & Laboratories and Others), and By Region - Market Trends, Analysis, and Forecast till 2030

Report Code: PMI471621 | Publish Date: August 2023 | No. of Pages: 168

Global MerTK Inhibitors Market Companies

  • Celon Pharma SA
  • Dong-A Socio Holdings Co Ltd
  • Eli Lilly and Co
  • Elsalys Biotech SA
  • F. Hoffmann-La Roche Ltd
  • HEC Pharm Co Ltd
  • Hope Biosciences Inc.
  • Incyte Corp
  • Meryx Inc.
  • Novithera SAS
  • Ono Pharmaceutical Co Ltd
  • Qurient Co Ltd
  • Rgenix Inc.
  • Signal Chem Lifesciences Corp
  • TamRx LLC.

Recent News:

  • According to research article by PubMed Central, Patients with primary EGFR mutations in non-small cell lung cancer (NSCLC) are now best treated with epidermal growth factor tyrosine kinase inhibitors, or EGFR-TKIs. After about a year, the patients do, however, inevitably become resistant to the EGFR-TKIs. The insensitivity of EGFR-TKI in non-small cell lung cancer is frequently caused by the activation of other receptor-mediated signaling pathways in addition to the acquisition of the EGFR T790M mutation. A poor prognosis for many tumors is linked to upregulation of the Tyro3-Axl-MERTK (TAM) family member Mer receptor tyrosine kinase (MERTK). The signaling pathways that EGFR shares, phosphoinositide 3-kinase (PI3K)/Akt and mitogen-activated protein kinase (MAPK), are triggered when particular ligands, like Gas6 and PROS1, bind to MERTK.