Amniotic Membrane Market Size, Share, By Product (Lyophilization and Cryopreserved), By Application (Ophthalmology, Surgical Wounds, and Others), and By End User (Hospitals, Specialized Clinics, Ambulatory Surgical Centres, and Research Centres & Laboratory), and By Region – Market Trends, Analysis and Forecast till 2034

Amniotic Membrane Market Size was valued at USD 4.0 Billion in 2024 and is expected to reach USD 12.8 Billion by 2034, growing at a CAGR of 13.60%

The amniotic membrane is the innermost layer of the placenta that helps the development of the fetus during the pregnancy is known as an amniotic membrane. It comprises a single epithelium layer, an avascular stromal matrix, and a thick basement membrane. Moreover, it has an anti-scarring effect and an anti-inflammatory effect. This membrane is a basement membrane substitute in the eye and acts as a temporary graft. Thus, it can be used in the treatment if various defects of the corneal epithelia. This is based on the lyophilized human amniotic membrane which allows the topical application to the ocular surface of endless quantities of amniotic membrane biological factors.

With the outbreak of COVID-19, various businesses are at the forefront of combating this pandemic. The pandemic has hindered the industrial supply chain and also disrupted the production segment. Governments across the countries have imposed strict lockdowns to limit the spread of disease. However, increasing investments by prominent players and other industries have created growth opportunities during this chaotic situation to fulfill the demand of suppliers. This report will quantify the impact of this pandemic on the amniotic membrane market.

Wound healing utilizes this amnion membrane, possessing a bacteriostatic and pain-reduction property. Growing awareness in the recent past has resulted in several transplants, thus increasing demand for these tissue-based products. As a result of this awareness, more donations have also taken place, fuelling market growth. Typically, indications for amniotic membranes are the reconstruction of the conjunctiva surface, pterygium excisions, and surgical wounds; corneal ulcers; pressure and venous leg ulcers; limbal stem cell deficiency; and regenerative medicine, amongst others.

Key Drivers of Target Market:   

Increasing Prevalence of Chronic Wounds

• The rising incidence of chronic wounds, including diabetic foot ulcers and venous leg ulcers, is one of the significant growth drivers for this market. These lead to a huge demand for better solutions to heal the wound; therefore, amniotic membranes have great potential for healing and tissue regeneration.

Advancements in Regenerative Medicine

• Significant steps forward have been made only recently in the field of regenerative medicine, which designs therapies that mobilize the body's own healing potential. The amniotic membrane is an intriguing matrix in tissue engineering and regeneration, as it provides a natural and biocompatible scaffold for tissue repair and regeneration. The continuous progress in regenerative medicine drives the demand for amniotic membrane-based therapies.

Restrains:

Regulatory Obstacles and Ethical Issues

• In certain areas, using tissues derived from humans, such as amniotic membranes, presents ethical and regulatory challenges. Tight laws governing tissue acquisition, processing, and safety might present problems for industry participants, restricting their capacity to supply goods in specific areas.

Amount-related factors

• The market may be constrained by the high expense of obtaining, preparing, and storing amniotic membranes. Overall, these treatments are more expensive because of the costs associated with upholding quality standards, carrying out clinical trials, and guaranteeing product safety, particularly in areas with little access to healthcare.

Opportunities:

Extension of Indications

• Originally, amniotic membranes were used for wound healing. But there's a rising movement to investigate their possibilities in other therapeutic domains, such as orthopaedics, dentistry, and ophthalmology. Amniotic membrane-based medicines are becoming more widely used, and researchers and businesses are looking into additional indications.

Development of sophisticated Processing Techniques

• The market is currently seeing the development of sophisticated processing techniques to improve the qualities and effectiveness of amniotic membrane goods. By maintaining the membrane's structural integrity and bioactive components, these methods should improve therapeutic results.

The market is segmented based on by Product, Application, End-User and Region.

Product Insights

• Lyophilization- This is a freeze-drying process for the amniotic membrane that involves sublimating its water content at very low temperatures and pressures. The formed product is dehydrated tissue that may then be preserved at room temperature for a long time.
• Cryopreserved- This segment currently dominates the market and takes a good deal of time in the said market. Cryopreserved membranes are stored in a cell culture medium with high concentrations of glycerol (~50%) at very low temperatures such as -80°C. This ensures that the histological and biological properties of the membrane remain preserved, hence applied in many ways with high efficiency.

 Application Insights

• Ophthalmology - This is a significant potential growth area, probably the one that holds the greatest growth potential. The amniotic membrane is applied to a corneal disease treatment, improvement of healing after surgical procedures, reduction of inflammation, and specific anti-scar properties in ophthalmic procedures.
• Surgical Wounds- This is the dominant application area at present. Amniotic membranes are used in the treatment of chronic wounds, including diabetic foot ulcers and burns. They help heal faster, relieve pain, and have antibacterial properties to reduce infections. The rising burden of chronic wounds worldwide fuels their growth.
• Others - Amniotic membranes are being explored for broader uses other than in ophthalmology and surgical wounds. Some of these areas of great promise are as follows:
• Dental surgeries: To enhance healing and reduce inflammation in procedures such as dental implants.
• Orthopedics: To promote the repair of cartilage or even its regeneration.
• Sports medicine: To speed up the healing process from sports injuries.
• Skin conditions: For the treatment of chronic skin conditions like bullous pemphigoid.

End User Insights

• Hospitals - hospitals are expected to be the largest, most potential consumers of amniotic membranes, as they entail the following factors. Large volume of surgeries and wound care procedures: No doubt, the hospital segment is likely to perform a wide range of procedures for which amniotic membrane applications can find use, such as ophthalmic surgeries and chronic wound treatments. Well-established infrastructure and resources: It is expected that such infrastructure and corresponding resources will already be available at hospitals for storing and utilizing amniotic membranes.
• Specialized Clinics - Specialist clinics in ophthalmology, dermatology, and wound care are another significant end-use segment. Such clinics deal with relatively narrow patient demographics for whom concentrated applications of amniotic membranes would be most beneficial.
• Ambulatory Surgical Centre - This segment increasingly uses amniotic membranes for various procedures, especially those in ophthalmology and orthopedics. This growth can be attributed to increased minimally invasive surgeries done in these centers.
• Research Centres & Laboratories- This is yet another area of immense potential and, therefore, also provides the impetus for future market expansion. Research centers and laboratories are presently working on the exploration of new applications of amniotic membranes and are undertaking a number of clinical trials to establish their efficacy in various medical conditions. All these efforts open the way for their broader adoption in clinical settings.

Regional Insights:

• North America: North America region holds a significant share of the global amniotic membrane market. The well-established and advanced healthcare infrastructure and superior medical facilities are major factors influencing this leading position. Increasing rate of adoption of new and innovative medical technologies. Growing awareness among the users and patients regarding the advantages of amniotic membranes. Favorable regulatory environment, promoting the growth of the market as a whole.
• Asia Pacific: this region is expected to grow fastest in the next few years. One driver for this surge is the rapid development of healthcare infrastructure across nations such as China and India. There is a rise in the prevalence of chronic wounds and eye diseases in this region. Growing awareness of amniotic membrane applications among healthcare professionals. Rise in disposable incomes, which shifts demand toward seeking advanced treatment options.
• Europe: Europe represents the other major market for amniotic membranes. Again, similar to North America, it is characterized by a developed health infrastructure coupled with a strong emphasis on newer technologies in healthcare. Moreover, increasing public investments in healthcare and rising disposable incomes in this region further accelerate the market growth.
• Latin America: Although the Latin American market for amniotic membranes is still in its nascent stage, it is expected to grow at a steady rate. This growth rate is influenced by factors such as increasing government and private investment in healthcare infrastructure, rising awareness about the use of amniotic membranes, and the succeeding prevalence of chronic wounds and eye diseases across the region.
• Middle East & Africa: The Middle East and Africa region has the smallest growth potential owing to several factors, including the following: Less-developed infrastructure related to health care compared to other regions. Surprisingly, less accessibility to advanced medical technologies. Lower disposable incomes, hence restricting the affordability of advanced treatments.

Amniotic Membrane Market Report Scope:

Attribute	Details
Market Size 2024	USD 4.0 Billion
Projected Market Size 2034	USD 12.8 Billion
CAGR Growth Rate	13.60%
Base year for estimation	2023
Forecast period	2024-2034
Market representation	Revenue in USD Billion & CAGR from 2024 to 2034
Market Segmentation	By Product - Lyophilization and Cryopreserved By Application - Ophthalmology, Surgical Wounds, and Others By End-User - Hospitals, Specialized Clinics, Ambulatory Surgical Centres, and Research Centres & Laboratory
Regional scope	North America - U.S., Canada Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific Latin America - Brazil, Mexico, Argentina, Rest of Latin America Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa
Report coverage	Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments Covered in the Report:

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2024 to 2034. For the purpose of this study, has segmented the Amniotic Membrane Market report based on By Product, Application, By End-User and Region:

Segmentation:

By Products:

• Lyophilization
•  Cryopreserved

By Application:

• Ophthalmology,
• Surgical Wounds
• Others

By End-User:

• Hospitals
• Specialized Clinics
• Ambulatory Surgical Centres
• Research Centres & Laboratory

By Region:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Russia
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • Israel
  • South Africa
  • Rest of Middle East & Africa

The key players operating the Amniotic Membrane Market include Amnio Technology, LLC, Applied Biologics LLC, Amniox Medical, Inc., AlloCure, Alliqua BioMedical, Inc., FzioMed, Inc., Skye Biologics, Inc., IOP Ophthalmics, CESCA THERAPEUTICS, Bellicum Pharmaceuticals, and Human Regenerative Technologies, LLC. 

• On June 25, 2024, The New Launch from AxoGen (AXGN) to Support Peripheral Nerve Protection AxoGen Avive+ Soft Tissue Matrix, AXGN's newest product, is now available for full use. Avive+ is a multi-layer, resorbable amniotic membrane allograft intended to be a barrier between soft tissues. It provides protection and temporary tissue separation during the critical phase of peripheral nerve healing.
• In April 2024, Xtant Medical is pleased to introduce SimpliGraftTM and SimpliMaxTM for acute and chronic wounds. A worldwide leader in medical technology, Xtant Medical Holdings, Inc. (NYSE American: XTNT) has announced the full commercial launch of two amniotic membrane allografts, SimpliGraftTM and SimpliMaxTM. The firm specializes in surgical treatments for spinal problems.

• Amnio Technology, LLC

• Company Overview
• Product Portfolio
• Key Highlights
• Financial Overview
• Business Strategies

• Applied Biologics LLC
• Amniox Medical, Inc.
• AlloCure
• Alliqua BioMedical, Inc.
• FzioMed, Inc.
• Skye Biologics, Inc.
• IOP Ophthalmics
• CESCA THERAPEUTICS
• Bellicum Pharmaceuticals
• Human Regenerative Technologies, LLC

“*” marked represents similar segmentation in other categories in the respective section.

Research Objective and Assumption

• Research Objectives
• Assumptions
• Abbreviations

Market Preview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Market Snippet, By Product
  • Market Snippet, By Application
  • Market Snippet, By End-User
  • Market Snippet, By Region
• Opportunity Map Analysis

Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
  • Drivers
  • Restraints
  • Market Opportunities
• Market Trends
• Product Launch
• Merger and Acquisitions
• Impact Analysis
• PEST Analysis
• Porter’s Analysis

Market Segmentation, Product, Forecast Period up to 10 Years, (USD Bn)

• Overview
  • Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
  • Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
  • Segment Trends
• Lyophilization
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Cryopreserved
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years

Market Segmentation, Application, Forecast Period up to 10 Years, (USD Bn)

• Overview
  • Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
  • Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
  • Segment Trends
• Ophthalmology
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Surgical Wounds
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Others
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years

Market Segmentation, End-User, Forecast Period up to 10 Years, (USD Bn)

• Overview
  • Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
  • Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
  • Segment Trends
• Hospitals
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Specialized Clinics
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Ambulatory Surgical Centres
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years
• Research Centres & Laboratory
  • Overview
  • Market Size and Forecast (USD Bn), and Y-o-Y Growth (%), Forecast Period up to 10 Years

Market Segmentation, By Region, Forecast Period up to 10 Years, (USD Bn)

• Overview
  • Market Value and Forecast (USD Bn), and Share Analysis (%), Forecast Period up to 10 Years
  • Y-o-Y Growth Analysis (%), Forecast Period up to 10 Years
  • Regional Trends
• North America
  • Market Size and Forecast (USD Bn), By Product, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By End-User, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
    • U.S
    • Canada
• Asia Pacific
  • Market Size and Forecast (USD Bn), By Product, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By End-User, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
    • India
    • Japan
    • South Korea
    • China
    • Rest of Asia Pacific
• Europe
  • Market Size and Forecast (USD Bn), By Product, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By End-User, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
    • UK
    • Germany
    • France
    • Russia
    • Italy
    • Rest of Europe
• Latin America
  • Market Size and Forecast (USD Bn), By Product, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By End-User, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
    • Brazil
    • Mexico
    • Rest of Latin America
• Middle East and Africa
  • Market Size and Forecast (USD Bn), By Product, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Application, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By End-User, Forecast Period up to 10 Years
  • Market Size and Forecast (USD Bn), By Country, Forecast Period up to 10 Years
    • GCC
    • Israel
    • South Africa
    • Rest of Middle East and Africa

Competitive Landscape

• Heat Map Analysis
• Company Profiles

• Amnio Technology, LLC
• Applied Biologics LLC
• Amniox Medical, Inc.
• AlloCure
• Alliqua BioMedical, Inc.
• FzioMed, Inc.
• Skye Biologics, Inc.
• IOP Ophthalmics
• CESCA THERAPEUTICS
• Bellicum Pharmaceuticals
• Human Regenerative Technologies, LLC

The Last Word

• Future Impact
• About Us
• Contact