Blood Cell Separation Market Size, Share, By Product (Consumables, and Instruments), Cell Type (Human Cells, Animal Cells, and Others), Technique (Centrifugation-based Cell Isolation, Surface marker-based Cell Isolation, and Filtration-based Cell Isolation), Application (Biomolecule Isolation, Cancer Research, Stem Cell Research, In-vitro Diagnostics, and Others), End-User (Research Laboratories and Institutes, Hospitals, and Others), and Region - Trends, Analysis and Forecast till 2035

• The blood cell separation market is expected to enlarge at USD 14.4 Billion by 2035.
• The market was valued at USD 7.2 Billion within 2024.
• Target market is developing at a CAGR of 7.2%.

Blood separation may be defined as the division of whole blood into its different components, such as, plasma platelets and red blood cells. Whole blood is often separated for diagnostic and therapeutic reasons, along with for research and to achieve this, scientists may use several blood separation techniques. Blood cell separation helps in developing personalized medicine, technological advancements, biopharmaceutical developments, stem cell therapy, cancer research, increased government funding, and public awareness, is fueling the blood cell separation market growth. Additionally, it provides effective treatment, improved diagnosis, better patient outcomes, and clinical cell therapy, thereby, fostering the market growth.

Repercussions of AI on this Market:

• Artificial intelligence (AI) is having a significant impact on blood cell separation by enabling automated, high-throughput analysis of blood cell images. This allows for faster, more accurate identification and classification of different blood cell types, which can lead to improved diagnosis of hematological disorders and earlier disease detection.
•  This is especially true when combined with traditional blood cell separation techniques such as centrifugation. In essence, AI is a powerful tool for analyzing and interpreting the detailed morphology of blood cells, providing valuable insights beyond simple cell counts.

Key Drivers of Target Market:

Blood Cell Separation Can Help in Cancer Research Thereby Propelling the Market Growth

Separating blood cells, especially circulating tumor cells (CTCs), help cancer researchers understand how cancer spreads and responds to treatment. This further helps to develop more effective and personalized treatment. Thus, blood cell separation helps in early cancer diagnosis, treatment selection, metastasis research, and treatment monitoring, driving the market growth.

• For instance, in June 2024, Bio-Rad Laboratories, Inc., a global leader in life science research and clinical diagnostics products, announced the launch of Celselect Slides 2.0 to enhance rare cell and circulating tumor cell (CTC) capture blood cell separation. Compatible with Bio-Rad’s Genesis Cell Isolation System, the latest version of Celselect Slides enabled the processing of greater volumes of liquid biopsy samples and offered the ability to capture and recover a greater number of CTCs for enumeration or use in downstream applications.

Restraints:

Cell Damage during Blood Cell Separation is Limiting the Market Expansion

A significant concern when separating blood cells is the possibility of cell damage, which most frequently manifests as hemolysis, i.e., the rupture of red blood cells and the release of its contents into the plasma, caused by excessive shear stress during the separation process, especially when centrifugation techniques, such as apheresis are used. This can degrade the quality of the separated blood components and have an impact on applications for downstream analysis or treatment.

• Counterbalance Statements: The solutions to overcome this problem involves using gentle techniques, such as density gradient centrifugation with carefully optimized solutions, which allow cells to separate based on its density while minimizing stress on the cell membranes.

Opportunities:

Amalgamation of Advanced Technologies for Blood Cell Separation Unlocks the Growth Potential

Future trends for blood cell separation may include microfluidics apheresis, label-free microfluidic structures, and high-throughput cytometry microsystems. Cell-based treatments may become more effective and of higher quality using microfluidics apheresis. Additionally, it can expedite the manufacturing of gene therapies and therapeutic cells.

Cancer cells can be separated from whole blood with the help of label-free microfluidic structures. With a high throughput, it may attain excellent separation efficiency. High-throughput cytometry microsystems are able to identify and measure the characteristics of blood cells. It can aid in the prevention of hematologic issues, such as leukastasis, occlusion, or sepsis.

• For instance, in May 2023, Sysmex Corporation launched its Clinical Flow Cytometry System Flow Cytometer XF-1600, Sample Preparation System PS-10, antibody reagents, and other related products in Japan. Sysmex’s flow cytometry portfolio made it possible, in combination with monoclonal antibody reagents, for laboratories to automate the entire process of flow cytometry testing from sample preparation to the reporting of measurement results of clinical FCM testing, which was performed for blood cell counting and separation.

The market is classified into product, cell type, technique, application, end-user, and region.

Product

On the basis of product type, the market is bifurcated into consumables and instruments. The consumables segment holds the biggest blood cell separation market share as they are frequently used and there is a growing investment in research and development.

• For instance, in May 2024, Applied Cells introduced its ground-breaking MARS Ingenuity Reagent kits, which was a consumable for fast and easy cell isolation. The newly launched product line had both Research Use Only (RUO) and Good Manufacturing Practice (GMP) grade reagents, tailored for application on Applied Cells’ proprietary MARS Bar platform. This combination offered a comprehensive solution for high quality immunomagnetic cell isolation, further advancing the cell therapy development.

Cell Type

Stemming from cell type, the market is divided into human cells, animal cells, and others. The human cell type dominates the market due to an expanding emphasis on cancer and human stem cell research, and the extensive use of isolated human cells in studies, the creation of biopharmaceuticals, and clinical trials.

Technique

Based on technique, the market is pigeonholed into centrifugation-based cell isolation, surface marker-based cell isolation, and filtration-based cell isolation. The centrifugation-based cell isolation is attributed to lead the market among the techniques due to its versatility and various applications. Additionally, it is used to separate cells by density, and is a key step in isolating blood cells, stem cells, and other types of cells.

• For instance, in July 2024, the Haier Biomedical Blood Banking Centrifuge LX-75L2400R had become the preferred choice in blood bank research and blood cell separation, due to its superior safety features, large storage capacity, exceptional separation efficiency, and intelligent operation. By overcoming the limitations of traditional equipment, it delivered groundbreaking performance with the capability of processing 16 bags of slurry in one operation and a lifespan of 15 years.

Application

Based on application, the market is catalogued into biomolecule isolation, cancer research, stem cell research, in-vitro diagnostics, and others. The biomolecule isolation segment holds the dominant blood cell separation market share as it is an essential stage in many biomedical research and therapeutic applications, such as medication development, personalized medicine, and disease diagnostics, as separating certain biomolecules from blood enable in-depth molecular study of a variety of medical problems.

End-User

The market is sub-segmented into research laboratories and institutes, hospitals, and others, on the premise of end user. The research laboratories and institutes are the end users who are expected to govern the market. This is due to the increased demand for cell separation in research, especially in cancer and stem cell research.

• For instance, in November 2022, NIHR Blood and Transplant Research Unit in Red Blood Cell Products, a research laboratory, initiated the RESTORE clinical trials (REcovery and survival of STem cell Originated REd cells). The researchers were studying the lifespan of the lab-grown cells, compared with normal blood cells from the same donor. This technology could revolutionize treatments for people with rare blood types, and blood disorders.

Region

Geographically, the market is branched into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.

North America: North America has the largest market share as compared to the other regions. This is due to well-established healthcare system, high levels of research and development, rising prevalence of chronic diseases, rising need for surgical procedures and development, and product of cell-based products in the region.

• For instance, in October 2024, Terumo Blood and Cell Technologies (Terumo BCT), a global leader in blood management solutions, launched the Reveos Automated Blood Processing System in the U.S. to help blood centers meet blood and platelet supply needs while helping its staff work more efficiently.

Europe: During the forecast period, Europe is expected to be the fastest growing region in the blood cell separation market due to the growing biotechnology sector, government support for healthcare research, and focus on cancer research and regenerative medicine in the region.

• For instance, in May 2024, Imec, a world-leading research and innovation hub in nanoelectronics and digital technologies, and Sarcura GmbH, an Austrian early-stage technology start-up, presented its proof-of-concept on-chip flow cytometer using integrated photonics. Published in Scientific Reports, part of the Nature Publishing Group, this innovation offered a unique platform for the detection and discrimination of human leukocytes and marked a significant stride towards cost-effective, scalable, and highly parallelized cell analysis.

Blood Cell Separation Market Report Scope:

Attribute	Details
Market Size 2025	USD 7.6 Billion
Projected Market Size 2035	USD 14.4 Billion
CAGR Growth Rate	7.2% (2025-2035)
Base year for estimation	2024
Forecast period	2025 – 2035
Market representation	Revenue in USD Billion & CAGR from 2025 to 2035
Regional scope	North America - U.S. and Canada Europe – Germany, U.K., France, Russia, Italy, Spain, Netherlands, and Rest of Europe Asia Pacific – China, India, Japan, Australia, Indonesia Malaysia, South Korea, and Rest of Asia Pacific Latin America - Brazil, Mexico, Argentina, and Rest of Latin America Middle East & Africa – GCC, Israel, South Africa, and Rest of the Middle East & Africa
Report coverage	Revenue forecast, company share, competitive landscape, growth factors, and trends

Segmentation:

By Product:

• Consumables
• Instruments

By Cell Type:

• Human Cells
• Animal Cells
• Others

By Technique:

• Centrifugation-based Cell Isolation
• Surface marker-based Cell Isolation
• Filtration-based Cell Isolation

By Application:

• Biomolecule Isolation
• Cancer Research
• Stem Cell Research
• In-vitro Diagnostics
• Others

By End User:

• Research Laboratories and Institutes
• Hospitals
• Others

By Region:

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • U.K.
  • France
  • Russia
  • Italy
  • Spain
  • Netherlands
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • Australia
  • Indonesia
  • Malaysia
  • South Korea
  • Rest of Asia Pacific
• Latin America
  • Brazil
  • Mexico
  • Argentina
  • Rest of Latin America
• Middle East & Africa
  • GCC
  • Israel
  • South Africa
  • Rest of the Middle East & Africa

The key players of this market are adopting strategies, such as magnetic based cell sorting, density gradient configuration, focus on precision medicine, and stem cell therapy. The companies operating in this market are GE HealthCare, BD, TERUMO BCT, INC., STEMCELL Technologies, Bio-Rad Laboratories, Inc., and others.

List of Key Players in the Market:

• BD
• TERUMO BCT, INC.
• STEMCELL Technologies
• Bio-Rad Laboratories, Inc.
• Beckman Coulter, Inc.
• Merck KGaA
• Thermo Fisher Scientific Inc.
• pluriSelect USA
• Miltenyi Biotec
• Fortis Life Sciences
• IBM
• Akadeum Life Sciences
• REPROCELL Inc.

• In September 2022, Akadeum Life Sciences, Inc., a global leader in buoyancy-based cell separation technology, announced a new early access program launch of an industry-first: the Microbubble Leukopak Human T Cell Isolation Kit. Leukopaks are blood bags that contain billions of extracted white blood cells and are frequently the starting point for CAR-T therapy and associated research. This was developed in order to give scientists an essential solution to biological and workflow challenges in the lab. The product combined unique advantages of microbubbles with a Buoyancy Activated Cell SortingTM (BACSTM) Separation Tube that is poised to transform large volume cell separation workflows.
• In June 2020, Corning Incorporated launched the Corning X-SERIES cell processing platform. The platform delivered, fast, sterile, automated, and efficient processing of human blood and blood products to obtain purified populations of immune cells for use in cell and gene therapy applications.

Analyst View:

The development of customized medicine, biopharmaceutical breakthroughs, stem cell treatment, and cancer research are all aided by blood cell separation, which drives the market's expansion. Furthermore, it offers clinical cell therapy, better patient outcomes, enhanced diagnostics, and effective treatment, all of which contribute to the target market expansion.

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Company Name	BD
Headquarter	Franklin Lakes, New Jersey, U.S.
CEO	Mr. Thomas Polen
Employee Count (2024)	73,000 Employees