Peptide Synthesis Market Overview
Peptide Synthesis Market was valued at US$ 5.5 Billion in 2024 and is projected to grow at a CAGR of 6.70% to reach US$ 5.7 Billion by 2034.
Peptide are amino acids which makes up certain proteins that are needed by skin. Addition of peptides helps in stimulation of skin for making collagen. Pituitary gland produces peptides. Peptidyl transferase act as an enzyme for peptide synthesis. Peptidyl transferase are located in larger ribosomal subunit where it help in catalyzing peptide bond formation. Examples of peptide includes, glutathione that stimulates growth of tissue, hormone oxytocin, pancreatic hormone insulin, melittin a honey bee venom, and glucagon a hyperglycemic factor. Peptide Synthesis is the formation of peptide bond between two amino acids. Peptide Synthesis refers to flexible chains up to 30-50 amino acids. The process of making short sequences of polypeptides by adding one amino acid at a time is called as peptide synthesis. Peptide Synthesis is used for creating specific sequences which represent epitopes of certain protein domains which may or may not be modified by phosphate groups. Peptide Synthesis is occurred by coupling of carboxyl group of incoming amino acid to N-terminus of growing peptide chain. Peptide Synthesis is the process where short sequences are prepared by addition of one amino acid at a time. Peptide Synthesis process is used for creating specific sequences which represent epitopes of certain protein domains which may or may not be modified by moieties like phosphate groups. Peptide Synthesis process allows to reduce the cause & length of chain branching. Peptide Synthesis takes place in ribosomes. Peptide are formed when condensation reaction takes place between carboxyl group of one amino acid & other amino group, ribosomes are the site of synthesis of proteins. However, rising research & development activities and wide use of peptide in pharmaceutical industries has given positive impact on target market growth.
Peptide Synthesis Market Dynamics
Rising research & development activities, and wide use in pharmaceutical & biotechnology industries is one of the leading factors for the Peptide Synthesis Market growth. Rise in diseases due to unhealthy lifestyle & urbanization has given rise in research & development activities and growth in pharmaceutical industries. Therapeutic peptides are widely used in pharmaceutical industries in medicines as it act as growth factors, hormones, ion channel ligands, neurotransmitters and anti-effective agents. Peptides are most commonly used in creating drugs for treating various diseases. Peptides are used in treating type 2 diabetes, high blood pressure and multiple sclerosis. Peptides are used in medicinal biotechnology as it possess antimicrobial, antioxidant, and anti-clotting effects among others. In pharmaceutical industries peptides has proved effective for multitude of disease state which includes, type 2 diabetes that are controlled by using licensed glucagon like peptide-1 receptor liraglutide, acromegaly is treated with octapeptide somatostatin analogues, and irritable bowel syndrome is managed with linaclotide. Therapeutic peptides act as growth factors, hormones, ion channel ligands, neurotransmitters and as anti-effective agents and thus used in medicines. Milk related bioactive peptides are commercially important. Membrane separation and chromatography techniques are applied in production of milk derived bioactive peptides. Peptide vaccines has wide variety of benefits as they allow vaccines to target specific epitopes while minimizing risk of allergic & autoimmune reactions. Use of peptides as immunogens offer advantages by lowering vaccine production cost & lead times. Solid phase peptide synthesis has major advantages like easy purification, precedent in synthesis of large peptides and rapid generation of linear peptide intermediates, etc. Synthetic peptides are used in research for polypeptide structural & functional studies, for antibody production, as hormone analogues, and as peptide hormones. Synthetic peptides are also used in designing novel enzymes, vaccines and drugs. Peptides like insulin are used as drug that controls metabolism of cyclosporine, sugar which suppresses rejection of organ after transplants. For instance, in 2021 Scientists at Imperial College London has developed new peptide manufacturing method ‘PEPSTAR’ which helps in improving efficiency of drug manufacturing processes and thus could produce cheaper medicines. Newly developed technique ‘PEPSTAR’ has ability to be scaled up for commercial use & extend to the production of other sequence defined polymers in various applications. Newly developed technique ‘PEPSTAR’ includes, quenching, coupling amino acid to ‘nanostar’ support, removing Fmoc protecting group, & filtering out reaction debris by membrane to effect nanostar sieving. However, growth in research & development activities, and wide use in pharmaceutical & biotechnology industries has boosts the demand for Peptide Synthesis Market.
Restrains:
Peptides alone are weakly immunogenic, has poor release properties, can easily go enzymatic degradation, etc. There are no any side effects of peptide but if it is misused then it causes headache, reaction at injection site like swelling & redness, increase in fluid retention, etc. Biggest limitation of peptide based drugs are poor oral adsorption, in vivo instability and membrane permeability which hinder their therapeutic effectiveness. However, some limitations and poor release properties of peptide synthesis may somewhat restrain the target market growth.
Peptide Synthesis Market Segmentation
The Peptide Synthesis market is segmented based on product, technology, application, end-users and region.
On the basis of product, the Peptide Synthesis market is segmented into Reagents & Consumables, Equipment and others. On the basis of technology, the target market is segmented into Hybrid Technology, Solid Phase Peptide Synthesis (SPPS), and Liquid Phase Peptide Synthesis (LPPS). On the basis of application, the target market is segmented into Infectious Diseases, Cardiovascular Disease, Respiratory Disease, and others. On the basis of end-users, the target market is segmented into Pharmaceutical & Biotechnology Companies, Research Institutes, Contract Research Organization (CRO), and others.
Regional Insights:
On region the Peptide Synthesis Market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The North America market is estimated to witness a significantly high revenue share over the forecast period, owing to growing population, especially in countries such as Europe and Asia Pacific, and technological advancements. Moreover, rising prevalence of chronic disease, rising incidence of cancer disease, well developed & robust healthcare and research infrastructure, rising investment in development of structural based drug designs, is anticipated to increase demand for Peptide Synthesis in the region.
Report Scope:
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Attribute |
Details |
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Base year for estimation |
2024 |
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Forecast period |
2024 – 2034 |
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Market representation |
Revenue in USD Billion & CAGR from 2024 to 2034 |
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Market Segmentation |
By Product - Reagents & Consumables, Equipment and others By Technology - Hybrid Technology, Solid Phase Peptide Synthesis (SPPS), and Liquid Phase Peptide Synthesis (LPPS) By Application – Infectious Diseases, Cardiovascular Disease, Respiratory Disease, and others By End-Users - Pharmaceutical & Biotechnology Companies, Research Institutes, Contract Research Organization (CRO), and others
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Regional scope |
North America - U.S., Canada Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific Latin America - Brazil, Mexico, Argentina, Rest of Latin America Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa |
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Report coverage |
Revenue forecast, company share, competitive landscape, growth factors, and trends |
Segments Covered in the Report:
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2022 to 2032. For the purpose of this study, has segmented the Peptide Synthesis Market report based on product, technology, application, end-users, and region:
Peptide Synthesis Market, By Product:
- Reagents & Consumables
- Equipment
- Others
Peptide Synthesis Market, By Technology:
- Hybrid Technology
- Solid Phase Peptide Synthesis (SPPS)
- Liquid Phase Peptide Synthesis (LPPS)
Peptide Synthesis Market, By Application:
- Infectious Diseases
- Cardiovascular Disease
- Respiratory Disease
- Others
Peptide Synthesis Market, By End-Users:
- Pharmaceutical & Biotechnology Companies
- Research Institutes
- Contract Research Organization (CRO)
- Others
Peptide Synthesis Market, By Region:
- North America
- U.S.
- Canada
- Europe
- Germany
- UK
- France
- Russia
- Italy
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia Pacific
- Latin America
- Brazil
- Mexico
- Rest of Latin America
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
Peptide Synthesis Market Key Players
The key players operating the Peptide Synthesis Market includes, Thermo Fisher Scientific, Kaneka Corporation, Merck KGaA, Bachem Holding AG, GenScript Biotech Corporation, Syngene, CEM Corporation, Lonza, Biotage AB, Novo Nordisk A/S, and others.
Peptide Synthesis Market Key Issues Addressed
Recent Development:
- In December 2022, Bachem Group has signed long term follow on contract for peptides. Contract has signed with total minimum order volume of CHF 1 billion over five year period from 2025 to 2029. Bachem Group is pursuing an investment program across all sites for expanding capacity. At Bubendorf site modern, large scale facility for manufacturing peptides & oligonucleotides is doubled with manufacturing capacity.
- In April 2022, CEM Corporation has launched the new ‘Liberty 2.0’ line of next generation automated microwave peptide synthesizers. Newly developed Liberty 2.0’ series continued to advance SPSS technology with development that result in enhanced peptide purity, exceptional automation reliability, and remarkable synthesis efficiency, it also features expanded reagent positions & automation options. Instrumentation in Liberty 2.0 line is featured with innovative headspace flushing process that fosters cleaner reaction vessel environment & help in providing unprecedented levels of peptide purity for sequences which exceeds 100 amino acids in length.
Peptide Synthesis Market Company Profile
- Bachem Holding AG*
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Thermo Fisher Scientific
- Kaneka Corporation
- Merck KGaA
- GenScript Biotech Corporation
- Syngene
- CEM Corporation*
- Lonza
- Biotage AB
- Novo Nordisk A/S
“*” marked represents similar segmentation in other categories in the respective section
Peptide Synthesis Market Table of Contents
- Research Objective and Assumption
- Preface
- Research Objectives
- Study Scope
- Years Considered for the study
- Assumptions
- Abbreviations
- Research Methodology
- Research data
- Primary Data
- Primary Interviews
- Primary Breakdown
- Key data from Primary Sources
- Key Thickness Insights
- Secondary Data
- Major Secondary Sources
- Secondary Sources
- Market Estimation
- Top-Down Approach
- Approach for estimating Market Share by Top-Down Analysis (Supply Side)
- Bottom-Up Approach
- Approach for estimating market share by Bottom-up Analysis (Demand Side)
- Market Breakdown and Data Triangulation
- Research Assumptions
- Market Purview
- Executive Summary
- Key Findings—Global Outlook for medical carts Strategies
- Key Questions this Study will Answer
- Market Snippet, By Product
- Market Snippet, By Technology
- Market Snippet, By Application
- Market Snippet, By End-Users
- Market Snippet, By Region
- Opportunity Map Analysis
- Executive Summary—3 Big Predictions
- Market Dynamics, Regulations, and Trends Analysis
- Market Dynamics
- Drivers
- Restrains
- Market Opportunities
- Market Trends
- DR Impact Analysis
- PEST Analysis
- Porter’s Five Forces Analysis
- Opportunity Orbit
- Market Investment Feasibility Index
- Macroeconomic Factor Analysis
- Market Dynamics
- Peptide Synthesis Market, By Product
- Overview
- Market Value and Forecast (US$ Bn), and Share Analysis (%), 2022 – 2032
- Y-o-Y Growth Analysis (%), 2022 – 2032
- Segment Trends
- Reagents & Consumables
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Equipment
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Others
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Overview
- Peptide Synthesis Market, By Technology, 2022 – 2032, (US$ Bn)
- Overview
- Market Value and Forecast (US$ Bn), and Share Analysis (%), 2022 – 2032
- Y-o-Y Growth Analysis (%), 2022 – 2032
- Segment Trends
- Hybrid Technology
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Solid Phase Peptide Synthesis (SPPS)
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Liquid Phase Peptide Synthesis (LPPS)
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Overview
- Peptide Synthesis Market, By Application, 2022 – 2032, (US$ Bn)
- Overview
- Market Value and Forecast (US$ Bn), and Share Analysis (%), 2022 – 2032
- Y-o-Y Growth Analysis (%), 2022 – 2032
- Segment Trends
- Infectious Diseases
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Cardiovascular Disease
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Respiratory Disease
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Others
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Overview
- Peptide Synthesis Market, By End-Users, 2022 – 2032, (US$ Bn)
- Overview
- Market Value and Forecast (US$ Bn), and Share Analysis (%), 2022 – 2032
- Y-o-Y Growth Analysis (%), 2022 – 2032
- Segment Trends
- Pharmaceutical & Biotechnology Companies
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Research Institutes
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Contract Research Organization (CRO)
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Others
- Overview
- Market Size and Forecast (US$ Bn), and Y-o-Y Growth (%), 2022 – 2032
- Overview
- Peptide Synthesis Market, By Region, 2022 – 2032, (US$ Bn)
- Overview
- Market Value and Forecast (US$ Bn), and Share Analysis (%), 2022 – 2032
- Y-o-Y Growth Analysis (%), 2022 – 2032
- Regional Trends
- North America
- Market Size and Forecast (US$ Bn), By Product, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Technology, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Application, 2022 – 2032
- Market Size and Forecast (US$ Bn), By End-Users, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Country, 2022 – 2032
- U.S.
- Canada
- Europe
- Market Size and Forecast (US$ Bn), By Product, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Technology, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Application, 2022 – 2032
- Market Size and Forecast (US$ Bn), By End-Users, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Country, 2022 – 2032
- UK
- France
- Germany
- Russia
- Italy
- Rest of Europe
- Asia Pacific
- Market Size and Forecast (US$ Bn), By Product, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Technology, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Application, 2022 – 2032
- Market Size and Forecast (US$ Bn), By End-Users, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Country, 2022 – 2032
- India
- Japan
- South Korea
- China
- Rest of Asia Pacific
- Overview
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- Latin America
- Market Size and Forecast (US$ Bn), By Product, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Technology, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Application, 2022 – 2032
- Market Size and Forecast (US$ Bn), By End-Users, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Country, 2022 – 2032
- Latin America
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- Brazil
- Mexico
- Rest of Latin America
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- Middle East & Africa
- Market Size and Forecast (US$ Bn), By Product, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Technology, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Application, 2022 – 2032
- Market Size and Forecast (US$ Bn), By End-Users, 2022 – 2032
- Market Size and Forecast (US$ Bn), By Country, 2022 – 2032
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- GCC
- Israel
- South Africa
- Rest of Middle East
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- Competitive Landscape
- Heat Map Analysis
- Market Presence and Specificity Analysis
- Company Profiles
- Thermo Fisher Scientific
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Kaneka Corporation
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Merck KGaA
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Bachem Holding AG
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- GenScript Biotech Corporation
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Syngene
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- CEM Corporation
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Lonza
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Biotage AB
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- Novo Nordisk A/S
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Performance
- Business Strategies
- The Last Word
- Future Impact
- About Us
- Contact
FAQs
The Peptide Synthesis Market is segmented into product, technology, application, end-users, and region.
Peptide Synthesis Market is driven by factors like rising research & development activities, and wide use in pharmaceutical & biotechnology industries.
By region, the Peptide Synthesis market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The North America market is estimated to witness a significantly high revenue share over the forecast period, owing to growing population, especially in countries such as Europe and Asia Pacific, and technological advancements.
The key players operating the Peptide Synthesis Market includes, Thermo Fisher Scientific, Kaneka Corporation, Merck KGaA, Bachem Holding AG, GenScript Biotech Corporation, Syngene, CEM Corporation, Lonza, Biotage AB, Novo Nordisk A/S, and others.