Organoids and Spheroids Market, By Type (Organoids, Spheroids), By Application (Personalized Medicine, Drug Toxicity and Efficacy Testing, Developmental Biology, Disease Pathology Studies, Regenerative Medicine, and Others), By End-User (Academic and Research Institute, Hospitals, Pharmaceutical Industries, Diagnostic Centers, and Others), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Trends, Analysis and Forecast till 2032

Report Code: PMI494722 | Publish Date: May 2023 | No. of Pages: 175

Organoids And Spheroids Market Overview

Organoids are referred as cells which are grown in 3D and form structural units that resembles organ in structure and function. Spheroids are spherical cellular units with cell aggregates and self-assembling in the environment which helps in preventing attachment to the flat surface. Organoids help in studying the cell interaction in an organ, interaction with environment, effect of disease and effect of drug on them. Organoids are generated from source of human cell like induced pluripotent cell (hIPSCs), embryonic stem cells (hESCs), and adult tissue-specific stem cells. Spheroids are generated from multicellular mixture of cells or single type cell. Spheroids are 3D cell cultures and grows on scaffold-free system while Organoids grows on scaffold-based system. Organoids and Spheroids are used in personalized medicine, drugs toxicity and efficacy testing which is essential in drug development process, regenerative medicine in which replacing or regenerating tissues, organs, human cells takes place to restore normal function, developmental biology which is the study of growth and development in plants. Wide variety of applications has fueled the Organoids and Spheroids Market growth.

Attributes

Details

Organoids and Spheroids Market Value (2022)

US$ 553.62 Mn

Organoids and Spheroids Market Projected Value (2032)

US$ 1234.51 Mn

Organoids and Spheroids Market CAGR (2022 – 2032)

8.4%

Organoids And Spheroids Market Dynamics

Rise in cancer disease and rate of urbanization

Rise in cancer disease and rate of urbanization is one of the leading factors for the Global Organoids and Spheroids Market growth. Urbanization is increasing worldwide. Urbanization has given rise in consumption of western food, processed food, frozen packed foods, which are unhealthy and affect the human health. Poor nutrition, pollution, communicable diseases are resulting due to rise in urban population. Urbanization has caused change in diet. Eating processed and unhealthy food affect the health causing chronic disease like heart disease, diabetes, obesity, high blood pressure, etc. Urbanization has changed the lifestyle of people like busy lifestyle, poor nutritive food, lack of exercise, unhealthy diet, which has led in prevalence of disease. Highest cancer incidence rate is observed in developed countries. Unhealthy lifestyle like Smoking, alcohol intake, low fruits and vegetable consumption, lack of exercise, low energy consumption, consumption of fat rich diet, high intake of animal derived food like red meat, rising obesity has given rise in cancer diseases. For instance, in 2020, according to (PMC), urban population was 36.6% to 44.8% in 1970-1994 and expected to increase till 61.1% till 2025. Around 70%-80% of colorectal cancer incidence in urban population occurs due to unhealthy lifestyle and environmental factors. For instance, in 2018, according to data published by United Nations in 2018, about 55% of the world’s population resided in urban areas, and it is projected that this percentage will increase over the forecast period. However, the growth in cancer disease and population in urban areas boosts the demand for Organoids and Spheroids market.

Technological advancement

The newly technological innovations or advancement in biomedical science has become the major factor for Organoids and Spheroids Market growth. Advanced development in 3D cell cultures of Organoids and Spheroids has become popular and thus revolutionized and offering the applications in disease modeling, drug discovery, cancer research. Advancement of Organoid Technology has application in Regenerative Medicine. To reproduce human tissues Organoid has provided the required technologies. Organoids and Spheroids are used in studying wide range of diseases like cancer, genetic diseases, infectious diseases. Advancement in 3D tissue culture has enable to study cell growth and interactions. Advanced 3D complex structures has improved accuracy and helps in facilitating in-vitro investigation of human diseases, personalized medical treatment and human development. Micropatterning, Microfluidic technique which are solutions of Microtechnology has improved the reproducibility of Organoids and Spheroids. Advancement in Organoids and Spheroids is increasing rapidly because of rising demand in research and development centers, pharmaceutical industries, biotechnology centers, etc. However, the advancement in technology and rising demand has fueled the Organoids and Spheroids market growth. For instance, in 2020, Tumor Spheroids and Organoids has provide promising applications in personalized medicine. The combination of 3D tumor models in personalized medicine like genomic, metabolomics and transcriptome will provide new possibilities for improved therapy of oncological diseases by new creation.

Restrains:

However, lack of high-fidelity cell types, lack of arealization and limited maturation may somewhat restrain the Organoids and Spheroids market growth.

Organoids And Spheroids Market Segmentation

 

Global Organoids and Spheroids Market is segmented based on type, application, end-user and region.

Type Insights

On the basis of Type Global Organoids and Spheroids Market is segmented into Organoids which are of two types, ESCs (embryonic stem cells) and ASCs (organ specific adult stem cells). Spheroids includes mammospheres, neurospheres, hepatospheres, MTCs (multicellular tumor spheroids) and embryoid bodies. Spheroids are dominating the market due to increase in technological advancement of 3D spheroid technology and rising demand in cancer research institute. In 2021, latest advancement in multicellular tumor spheroid (MCTs) generation for drug screening has offered advantage in designing 3D solid tumor model.

Application Insights

On the basis of Application Global Organoids and Spheroids Market is segmented into personalized medicine, drug toxicity and efficacy testing, developmental biology, disease pathology studies, regenerative medicine and others. Drug toxicity and efficacy testing are dominating the market because of increase in prevalence of disease like cancer due to smoking, lack of exercise, obesity, etc. In 2019, the application of Cancer Organoid Model used for Drug Screening and Personalized Therapy. By using cancer organoids in drug screening system applied to estimate most beneficial drug for an individual.

End-User Insights

On the basis of End-User Global Organoids and Spheroids Market is segmented into academic & research institute, hospitals, pharmaceutical industries, diagnostic centers and other. Academic and Research Institute are dominating the market due to rising use of organoids and spheroids in cancer drug research, biochemical studies, imaging, etc. In 2019, the use of cancer organoids in development and advancement in disease models for research in cancer and drug screening is expanding in preclinical cancer research and basic field.

Regional Insights:

Disclaimer: This data is only a representation. Actual data may vary and will be available in the report.

On region the Global Organoids and Spheroids Market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The North America market is estimated to witness a significantly high revenue share over the forecast period, owing to growing population, especially in countries such as Europe and Asia Pacific, and technological advancements. Moreover, rising prevalence of cancer disease, increase in growth and investment in research and development activities, rising adoption of organoid models, spheroid models for cancer research and biotechnology sector in U.S. and Canada is anticipated to increase demand for Organoids and Spheroids in the region.

Report Scope:

Attribute

Details

Base year for estimation

2022

Forecast period

2022 – 2032

Market representation

Revenue in USD Million & CAGR from 2022 to 2032

Market Segmentation

By Type- Organoids and Spheroids

By Application - Personalized Medicine, Drug Toxicity and Efficacy Testing, Developmental Biology, Disease Pathology Studies, Regenerative Medicine, and others

By End-User - Academic and Research Institute, Hospitals, Pharmaceutical Industries, Diagnostic Centers, and others

Regional scope

North America - U.S., Canada

Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe

Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific

Latin America - Brazil, Mexico, Argentina, Rest of Latin America

Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa

Report coverage

Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments Covered in the Report:

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2022 to 2032. For the purpose of this study, has segmented the Global Organoids and Spheroids Market report based on type, application, end-user and region:

 

Global Organoids and Spheroids Market, By Type:

  • Organoids
  • Spheroids

Global Organoids and Spheroids Market, By Application:

  • Personalized Medicine
  • Drug Toxicity and Efficacy Testing
  • Developmental Biology
  • Disease Pathology Studies
  • Regenerative Medicine
  • Others

Global Organoids and Spheroids Market, By End-User:

  • Academic and Research Institute
  • Hospitals
  • Pharmaceutical Industries
  • Diagnostic Centers
  • Others

Global Organoids and Spheroids Market, By Region:

      • North America
          • U.S.
          • Canada
      • Europe
          • Germany
          • UK
          • France
          • Russia
          • Italy
          • Rest of Europe
      • Asia Pacific
          • China
          • India
          • Japan
          • South Korea
          • Rest of Asia Pacific
      • Latin America
          • Brazil
          • Mexico
          • Rest of Latin America
      • Middle East & Africa
          • GCC
          • Israel
          • South Africa
          • Rest of Middle East & Africa

Organoids And Spheroids Market Key Players

The key players operating the Global Organoids and Spheroids Market includes,

InSphero AG

It provides biological relevance which is superior in, in-vitro testing, offers biological, organotypic, in-vitro 3D microtissues in drug testing which are highly predictive.

AMS Biotechnology

A leading company which offers products like western blots, assay kits, microarrays, cDNA, RNA,  for immunology, proteomics and genomics. 

3Dnmaics Inc.

It is the biotechnology company and developer of stem cell stem cell engineering technology which helps in improving human health.

STEMCELL Technologies

It is the Canadian Biotechnology Company and developer of cell separation systems, cell culture media and provides reagents and instruments for life sciences research.

3D Biotek LLC.

It is the high-tech biomedical engineering company. It provides 3D cell culture products of finest quality.

DefiniGEN Ltd.

It provides wide range of human cell products like mature hepatocytes, intestinal organoids, pancreatic cells, etc. which are terminally differentiated.

Lonza

It is the multinational manufacturing company for nutritional sectors, biotechnology, pharmaceutical, consumer products, academic & government research institutes, etc.

Prellis Biologics

It is the company which develops tools for creating 3D printed organs and also the developer of bio-printing technology used in recreating, engineer human tissues, in in-vitro.  

Corning Inc.

It is the global leading innovator in material science and develops new products in automation, 3D cell culture, drug discovery and other.

ATCC

It is the non-profitable organization which helps in collection, storing and distributing the standard reference cell lines, micro-organisms, and provides material for research and development centers.

PeproTech Inc.

It is the manufacturing company which provides high quality products like recombinant cytokines and support cellular therapy, regenerative medicine and science research that advance human health & scientific discovery.

Hubrecht Organoid Technology

It is the biotechnology company that provides development, companion diagnostics, preclinical patient stratification, clinical trials, predictive biomarker discovery, regenerative medicine and personalized medicine.

Thermofisher Scientific Inc.

It offers the product like cell culture products, analyzers, microbiology products, spectrophotometers, chromatography systems, fermenters, and other.

 Recent Development

  • In February 2022, Corning Inc., launched the new ‘Corning Matribot Bioprinter’, which is the device that allows printing & dispensing with Corning Matrigel Matrix, temperature sensitive hydrogels and collagen without using ice-buckets and cold blocks. Corning Matrigel Matrix is used in 3D cell culture by providing signaling cues and structure in 3D & Organoid models.
  • In February 2021, Thermofisher Scientific has launched new product ‘Gibco Human Plasma-Like Medium’ (HPLM), which is the first cell culture medium in market. This newly launched product provides the ability for researcher in studying the effect of physiologically relevant cell media on specific research applications like cancer and other diseases also it provides realistic view of cell growth in human body.

Organoids And Spheroids Market Company Profile

  • Corning Inc.*
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • InSphero AG
  • AMS Biotechnology
  • 3Dnmaics Inc.
  • STEMCELL Technologies
  • 3D Biotek LLC.
  • DefiniGEN Ltd.
  • Lonza
  • Prellis Biologics
  • ATCC
  • PeproTech Inc.
  • Hubrecht Organoid Technology
  • Thermofisher Scientific Inc.*

“*” marked represents similar segmentation in other categories in the respective section

Organoids And Spheroids Market Table of Contents

  1. Research Objective and Assumption
    • Preface
    • Research Objectives
    • Study Scope
    • Years Considered for the study
    • Assumptions
    • Abbreviations
  2. Research Methodology
    • Research data
    • Primary Data
      • Primary Interviews
      • Primary Breakdown
      • Key data from Primary Sources
      • Key Thickness Insights
    • Secondary Data
      • Major Secondary Sources
      • Secondary Sources
    • Market Estimation
    • Top-Down Approach
      • Approach for estimating Market Share by Top-Down Analysis (Supply Side)
    • Bottom-Up Approach
      • Approach for estimating market share by Bottom-up Analysis (Demand Side)
    • Market Breakdown and Data Triangulation
    • Research Assumptions
  3. Market Purview
    • Executive Summary
    • Key Findings—Global Outlook for medical carts Strategies
      • Key Questions this Study will Answer
      • Market Snippet, By Type
      • Market Snippet, By Application
      • Market Snippet, By End-User
      • Market Snippet, By Region
    • Opportunity Map Analysis
    • Executive Summary—3 Big Predictions
  4. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restrains
      • Market Opportunities
      • Market Trends
    • DR Impact Analysis
    • PEST Analysis
    • Porter’s Five Forces Analysis
    • Opportunity Orbit
    • Market Investment Feasibility Index
    • Macroeconomic Factor Analysis
  5. Global Organoids and Spheroids Market, By Type
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2022 – 2032
      • Y-o-Y Growth Analysis (%), 2022 – 2032
      • Segment Trends
    • Organoids
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Spheroids
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
  6. Global Organoids and Spheroids Market, By Application, 2022 – 2032, (US$ Mn)
    • Overview                                      
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2022 – 2032
      • Y-o-Y Growth Analysis (%), 2022 – 2032
      • Segment Trends
    • Personalized Medicine
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Drug Toxicity and Efficacy Testing
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Developmental Biology
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Disease Pathology Studies
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Regenerative Medicine
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Others
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
  7. Global Organoids and Spheroids Market, By End-User, 2022 – 2032, (US$ Mn)
    • Overview                                      
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2022 – 2032
      • Y-o-Y Growth Analysis (%), 2022 – 2032
      • Segment Trends
    • Academic and Research Institute
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Hospitals
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Pharmaceutical Industries
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Diagnostic Centers
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
    • Others
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2022 – 2032
  8. Global Organoids and Spheroids Market, By Region, 2022 – 2032, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2022 – 2032
      • Y-o-Y Growth Analysis (%), 2022 – 2032
      • Regional Trends
    • North America
      • Market Size and Forecast (US$ Mn), By Type, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Application, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By End-User, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Country, 2022 – 2032
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast (US$ Mn), By Type, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Application, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By End-User, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Country, 2022 – 2032
        • UK
        • France
        • Germany
        • Russia
        • Italy
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast (US$ Mn), By Type, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Application, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By End-User, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Country, 2022 – 2032
        • India
        • Japan
        • South Korea
        • China
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast (US$ Mn), By Type, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Application, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By End-User, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Country, 2022 – 2032
        • Brazil
        • Mexico
        • Rest of Latin America
    • Middle East & Africa
      • Market Size and Forecast (US$ Mn), By Type, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Application, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By End-User, 2022 – 2032
      • Market Size and Forecast (US$ Mn), By Country, 2022 – 2032

 

        • GCC
        • Israel
        • South Africa
        • Rest of Middle East
  1. Competitive Landscape
    • Heat Map Analysis
    • Market Presence and Specificity Analysis
  2. Company Profiles
  • InSphero AG
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • AMS Biotechnology
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • 3Dnmaics Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • STEMCELL Technologies
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • 3D Biotek LLC.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • DefiniGEN Ltd.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Lonza
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Prellis Biologics
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Corning Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • ATCC
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • PeproTech Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Hubrecht Organoid Technology
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Thermofisher Scientific Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  1. The Last Word
    • Future Impact
    • About Us
    • Contact

FAQs

The Organoids and Spheroids Market is segmented into Type, application, end-user, and region.

Organoids and Spheroids Market is driven by factors like rise in cancer diseases, rate of urbanization, and technological advancement.

By region, the Organoids and Spheroids market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The North America market is estimated to witness a significantly high revenue share over the forecast period, owing to growing population, especially in countries such as Europe and Asia Pacific, and technological advancements.

The key players operating the Organoids and Spheroids Market includes, InSphero AG, AMS Biotechnology, 3Dnmaics Inc., STEMCELL Technologies, 3D Biotek LLC., DefiniGEN Ltd., Lonza, Prellis Biologics, Corning Inc., ATCC, PeproTech Inc., Hubrecht Organoid Technology, Thermofisher Scientific Inc.