Mice Model Market By Mice Type (Inbred, Outbred, Knockout, Hybrid and Others), By Technology (CRISPR, Microinjection, Embryonic Stem Cell Injection, Nuclear Transfer and Others), By Application (Research & Development, Infectious Disease, Cancer, Cardiovascular Diseases, Genetic Diseases and Others), By End-User (Pharmaceutical, Biotechnology, Cosmetics, Contract Research Organizations (CRO) and Others) and By Region- Trends, Analysis and Forecast till 2030

Mice Model Market accounted for USD 1.54 Billion in 2020 and is estimated to be USD 2.77 Billion by 2030 and is anticipated to register a CAGR of 6.10%.

A mouse model is a laboratory model that is used to study human physiology, biomedical science, and illness. It is utilized to research complicated conditions like hypertension and atherosclerosis. Mice are important in studies since they are genetically identical to humans in 95 percent of cases. The use of mouse models has expanded as a result of technological developments in gene editing, which has greatly benefited scientists in the discovery and development of innovative medications. These models are widely utilized in research studies in a variety of domains, including oncology and immunology. The market for genetically engineered humanized mice models has grown in response to the growing need for tailored medications.  

Impact of Covid-19 pandemic on market

The coronavirus epidemic that has resulted in the continuing COVID-19 pandemic is an unparalleled public health threat. Due to humans lack of pre-existing immunity to SARS-CoV-2, there is a growing need for vaccines and therapeutic medicines to combat the current pandemic and avoid the reemergence of COVID-19. Due to the requirement to conduct research tests, the demand for humanized ACE2 mice models is increasing. As a result, government and scientific research institutes are likely to expand their research investments in the development of COVID-19 vaccines and therapies.

Advances in gene editing techniques

The growth of the mice model business will be aided by advances in gene editing techniques. The CRISPR-associated protein (Cas9) technology, also known as clustered regularly interspaced short palindromic repeats, has revolutionized genome editing. Several unique applications of CRISPR/Cas9 in a wide spectrum of disorders have proved its efficacy, and in-vivo mouse models have been employed extensively. For example, using the CRISPR system to somatic cells of adult mice via viral delivery led to the creation of an Eml4-Alk-driven lung cancer mouse model to examine disease features. Incorporating Cas9 into mouse zygotes has also resulted in transgenic mice, which may be used to study the pathophysiology of cardiovascular disorders. The CRISPR-Cas9 system was also utilized to create Kcnj13 mutant mice for research into ocular illnesses.

Inbred mice model market sales exceeded, owing to the increased use of inbred mice in pharmacology and cardiovascular disease research, as well as to analysis of the reactions of monoclonal antibodies. Inbred mice have been proven to be effective instruments in genetic research of complicated disorders, increasing inbred mouse demand. Due to the uniformity of the genetic background, they are also used in transgenic research. Furthermore, inbred mice are less expensive than mutant humanized mice. They have a fully developed immune system, are genetically stable, and are cost-effective.

The Mice Model Market report segments the market on the basis of mice type, technology, application, end-user and region.

On the basis of Mice Type, the Mice Model Market is segmented into Inbred, Outbred, Knockout, Hybrid and Others. On the basis of Technology, the target market is segmented into CRISPR, Microinjection, Embryonic Stem Cell Injection, Nuclear Transfer and Others. Based on Application, the market is segmented into Research & Development, Infectious Disease, Cancer, Cardiovascular Diseases, Genetic Diseases and Others. Based on End-User, the market is segmented into Pharmaceutical, Biotechnology, Cosmetics, Contract Research Organizations (CRO) and Others.

Regional Insights:

In the region, the Mice Model Market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The United States dominated the North American mice model market due to the high frequency of chronic diseases such as diabetes and viral diseases. Several research organizations in the country are concentrating on the development of effective therapeutic medications for viral illness therapy. In the United States, high-throughput mutagenesis projects are producing a huge number of mutant mouse models through the Knockout Mouse Project (KOMP). In order to address the need and supply of mouse models, the Mutant Mice Regional Resource Center (MMRRC) in the United States serves as a repository for mouse strains that are important for use in biomedical research. The presence of well-established industry players in the country, as well as state-of-the-art healthcare facilities, would further fuel market demand.

Segments Covered in the Report:

This report forecasts revenue growth at , regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2019 to 2029. For the purpose of this study, has segmented the Mice Model Market report based on mice type, technology, application, end-user and Region.

Recent Highlights:

• Merck granted GenOway exclusive worldwide rights to its basic CRISPR/Cas9 portfolio in the rodent industry in 2020.
• Taconic and the University of Texas Medical Branch signed an agreement in 2020 to distribute humanised ACE2 mice for COVID-19 research.
• The Jackson Laboratory began producing ACE2 mice in 2020 in order to aid COVID-19 research.
• Oragenics Inc. and Aragen Bioscience have agreed to collaborate on the development of TerraCoV2, a SARS-CoV-2 (COVID-19) vaccine candidate, in 2020.
• Innovive announced plans to expand its manufacturing facilities in North Sioux City, South Dakota, in 2020. (US).

Mice Model Market, By Region:

• North America
  • Middle East & Africa
    • • GCC
      • Israel
      • South Africa
  • Latin America
    • • Brazil
      • Mexico
      • Rest of Latin America
  • Asia Pacific
    • • China
      • India
      • Japan
      • South Korea
      • Rest of Asia Pacific
  • Europe
    • • Germany
      • UK
      • France
      • Russia
      • Italy
      • Rest of Europe
  • U.S.
  • Canada

Rest of Middle East & Africa

The key players operating in the Mice Model Market include Charles River Laboratories, (US) The Jackson Laboratory (US), Taconic Biosciences, Inc. (US), Envigo (US), JANVIER LABS (France), genOway (France), PolyGene (Switzerland), Crown Biosciences (US), TransCure bioservices (France), Ingenious Targeting Laboratory (US), Cyagen Biosciences (US), GVK BIO (India), The Andersons, Inc. (US), Innovive (US), Allentown, LLC (US), FENGSHI Group (China), Ozgene Pty Ltd. (Australia), and Harbour Biomed (US).

Taconic Biosciences, Inc.

Taconic Biosciences is a private biotechnology firm that specializes in genetically altered mice and rat models, as well as microbiome, immuno-oncology, and integrated model design and breeding services. Taconic Farms, the company's original name, was formed in 1952. Taconic Biosciences released the first commercially developed NASH diet-induced (nonalcoholic steatohepatitis) mice model in July 2019.

• Charles River Laboratories
• The Jackson Laboratory
• Taconic Biosciences, Inc.
• JANVIER LABS
• genOway
• PolyGene
• Crown Biosciences
• TransCure bioservices
• Ingenious Targeting Laboratory
• Harbour Biomed