Global Transfection Reagents And Equipment Market Overview
Transfection is the process of introducing nucleic acids in the eukaryotic cells, where genetic material such as DNA, RNA, supercoiled Plasmid DNA, proteins and antibodies are transfected. Transfection helps to find out the gene expression, protein coding, and gene function modulation in case of cancer. Thus, it helps to find out the basic biosciences research like differentially expressed genes, gene ontology, pathway analysis, identification of small molecules based on whether the gene expression is upregulated or downregulated.
There are three methods for the introduction of foreign genetic material such as biochemical, physical and viral methods. The biochemical method is further classified into calcium phosphate, lipofection DEAE-dextran, and dendrimer. However, physical methods consist of electroporation, nucleofection and microinjection. Viral method includes Adenoviral Vectors Transfection Reagents and Equipment method. Genetic material can also be introduced into the cell by viruses as a carrier. Adenoviral vectors are commonly used in the vector transfection.
Impact of COVID – 19 on the market
With the outbreak of the COVID-19, various businesses are at the forefront to combat this pandemic. The pandemic has hindered the industrial supply chain and also disrupted the product segment. Government across the countries has imposed strict lockdown to limit the spread of disease. The transfection reagent and equipment scope and applications are increasing very widely, due to increasing number of corona virus cases, as sample kits requires transfection reagents to detect the virus. Further, due to increase in COVID-19 cases, key players of transfection reagents are increasing their production volume, to support the population. This report will quantify the impact of this pandemic on the transfection reagents and equipment market.
Global Transfection Reagents And Equipment Market Dynamics
The cells which are transiently transfected takes around 24 – 96 hours post transfection and the mRNA is expressed within minutes after transfection that means it takes very less time to show the results. The main application of transfection reagent and equipment is used in studying the effect of gene expression, gene products, gene silencing and largely producing recombinant proteins. Highly increasing application like gene expression studies, protein production, transgenic models, therapeutic delivery, cancer research and biomedical research is expected to foster the transfection reagents and equipment market. Transfection of mammalian cells is mostly effective in the production of recombinant protein with proper folding and post-translational modification.
Technological advancements in transfection technology
The transfection reagents and equipment market has seen diverse technological achievements in equipment as well as reagents, to address the demands of biotechnology and researchers and biopharmaceutical associations. Increasing demand of synthetic genes, R & D investment and research activities, emerging economics drives the target market. For instance, in July 2020, Polyplus-transfection(R) SA, the leading biotechnology company that supports the gene and cell therapy market by supplying innovative transfection solutions, announced the launch of the industry’s first GMP-compliant residual test for its PEIpro (R) product portfolio, transfection reagents designed for process development, pre-clinical, clinical and commercial lentivirus and adeno-associated virus (AAV) production for cell & gene therapies. Transfection promotes the process of introducing genetic material into eukaryotic cell to enable the production or expression of proteins using cell’s machinery.
Nevertheless, the overall market is anticipated to rise at a considerable rate during the upcoming years, at steady growth rate.
However, factors such as high cost of transfecting reagent and equipment, risk associated with the process of inserting genetic material into the cell, the cytotoxic effects associated with process, and the growing applications of home brew reagents hampers growth of the global market to a certain extent.
Global Transfection Reagents And Equipment Market Segmentation
The global transfection reagents and equipment market is segmented based on the product, method, application, end-user, and region.
On basis of products, the target market is segmented into reagents and equipment. Based on methods, the target market is classified into biochemical, physical and viral methods. However, the biochemical method is further classified into calcium phosphate, lipofection DEAE-dextran, and dendrimer. The physical method is sub-segmented into electroporation, nucleofection, and microinjection. Whereas, the electroporation segment is expected to dominate the transfection reagents and equipment market. The viral method is sub-segmented into adenoviral vectors.
Depending upon application, the worldwide market is classified into biomedical research, gene expression studies, cancer research, transgenic models, protein production, and therapeutic delivery. In 2019, gene expression studies has shown the largest growth for transfection reagent and equipment. This has help in the development of large genomic pool and which will represent the results as clinical workflow. Biomedical research also showed the fastest growth in the forecast period. Gene mutation identification and library screening has made the considerable contributions in the biomedical research.
Based upon the end users, the global market is divided into academics & research institutes and pharmaceutical & biotechnology companies.
Regional Insights:
According to the regional, market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America is expected to account for the largest share of the transfection reagents and equipment’s market, due to rising prevalence of various cancers such as cervical cancer, breast cancer, colon cancer and prostate cancer. Further, the government of North America is highly increasing their investments in the biological research, genomics research and in the production of therapeutic proteins, which in turn boosts growth of the target market in this region.
Europe and the Asia Pacific are also expected to show significant growth in the transfection reagents and equipment market. Companies present in Europe are focused on targeted drug delivery, nanomedicine in diagnostics and clinical trials, which is expected to augment the target market. Asia Pacific is also expected to grow their market by creating the favorable environment for enrolling new manufacturers and increasing their healthcare expenditure. The most important reason behind the growth of transfection reagents and equipment growth in Asia Pacific is their ongoing clinical trials for drug discovery companies.
Detail Segmentation:
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Attribute |
Details |
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The base year for estimation |
2019 |
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Forecast Period |
2019 - 2029 |
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Market Representation |
Revenue in USD Million & CAGR from 2019-2029 |
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Market Segmentation |
By Product - Reagents and Equipment By Method - Biochemical Methods, Physical Methods and Viral Methods By End User - Pharmaceutical & Biotechnology Company By Application - Biomedical Research, Gene Expression Studies, Cancer Research, Transgenic Models, Protein Production, Therapeutic Delivery By Region - North America, Europe, Asia Pacific, Latin America, and Middle East & Africa |
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Regional Scope |
North America - U.S., Canada Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific Latin America - Brazil, Mexico, Argentina, Rest of Latin America Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa |
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Report Coverage |
Revenue forecast, company share, competitive landscape, growth factors, and trends |
Segments covered in the report:
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends and opportunities in each of the sub-segments from 2019 to 2029. For the purpose of this study, has segmented the global transfection reagents and equipment market report based on products, methods, application, end-user, and region.
Transfection Reagents and Equipment Market, By Products:
- Reagents
- Equipments
Transfection Reagents and Equipment Market, By Methods:
- Biochemical methods
- calcium phosphate
- Lipofection DEAE-dextran
- dendrimer
- Physical methods
- Electroporation
- Nucleofection
- Microinjection
- Viral methods
- Adenoviral vectors
Transfection Reagents and Equipment Market, By Application:
- Biomedical Research
- Gene Expression Studies
- Cancer Research
- Transgenic Models
- Protein Production
- Therapeutic Delivery
Transfection Reagents and Equipment Market, By End User:
- Academics and Research Institutes
- Pharmaceutical and Biotechnology companies
Transfection Reagents and Equipment Market, By Region:
- North America
- U.S.
- Canada
- Europe
- Germany
- UK
- France
- Russia
- Italy
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- South Korea
- Rest of Asia Pacific
- Latin America
- Brazil
- Mexico
- Rest of Latin America
- Middle East & Africa
- GCC
- Israel
- South Africa
- Rest of Middle East & Africa
Global Transfection Reagents And Equipment Market Key Players
Key players in the transfection reagent and equipment market include Thermo Fisher Scientific, Promega Corporation, Lonza, QIAGEN, F. Hoffmann-La Roche Ltd., Bio-Rad Laboratories, Merck KGaA, OriGene Technologies, MaxCyte, Polyplus-transfection SA. These key players have adopted various strategies such as new product launches, merges and acquisitions to expand their market presence. For instance, on April 2019, Lonza launched their portfolio called CellBio. CellBio generally works in the Transfection services and cell-line expansion, which is expected to grow the market.
Global Transfection Reagents And Equipment Market Company Profile
- Thermo Fisher Scientific*
- Company Overview
- Product Portfolio
- Key Highlights
- Financial Overview
- Business Strategies
- Promega Corporation
- Lonza
- QIAGEN
- F. Hoffmann-La Roche Ltd.
- Bio-Rad Laboratories Inc.
- Merck KGaA
- OriGene Technologies
- MaxCyte
- Polyplus transfection
“*” marked represents similar segmentation in other categories in the respective section
FAQs
The global transfection reagents and equipments market is segmented based on product, methods, application, end users and region.
Rising initiatives of government bodies as well as increasing adoption of cloud-based solutions boost the growth of market.
North America is expected to account for the largest share of the transfection reagents and equipment’s market, due to rising prevalence of various cancers such as cervical cancer, breast cancer, colon cancer and prostate cancer.
Key players have adopted various strategies such as new product launches, merges and acquisitions to expand their market presence. For instance, on April 2019, Lonza launched their portfolio called CellBio. CellBio generally works in the Transfection services and cell-line expansion, which is expected to grow the market.