In-Vitro Toxicology/Toxicity Testing Market By Product and Service (Consumables, Assays (Bacterial Toxicity Assays, Enzyme Toxicity Assays, Cell-based Elisa and Western Blots, Receptor-binding Assays, Tissue Culture Assays, and Other Assays), Equipment, Software, and Services), By Method (Cellular Assays, Biochemical Assays, In Silico Models, and Ex Vivo Models), By Toxicity Endpoint (ADME, Skin Irritation, Corrosion and Sensitization, Genotoxicity Testing, Cytotoxicity Testing, Ocular Toxicity, Organ Toxicity, Phototoxicity Testing, Dermal Toxicity, and Other Toxicity Endpoints & Tests), By Technology (Cell Culture Technologies, High-throughput Technologies, Toxicogenomics), By Industry (Pharmaceuticals and Biopharmaceuticals, Cosmetic and Household Products, Food, and Chemicals), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Trends, Analysis and Forecast till 2030

In-vivo toxicology/Toxicity Testing Market accounted for US$ 22.7 billion in 2020 and is estimated to be US$ 55.83 billion by 2030 and is anticipated to register a CAGR of 10.5%.

In vitro toxicity testing is the scientific analysis of the effects of toxic chemical substances on cultured bacteria or mammalian cells. In vitro testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as therapeutic drugs, agricultural chemicals and food additives.

The major factor driving the growth of the in-vitro toxicity testing market are opposition to animal testing, technological advancements, and increasing R&D expenditure to detect toxicity at an early stage during drug development. In addition, the factors such as ethical issues and pressure from animal activists groups concerning the use of animals for testing, ban on animal testing on cosmetic products, support from regulatory bodies regarding the approval of in vitro tests, low costs associated with in vitro toxicology testing, and advancements in vitro methodologies are driving the growth of the in-vitro toxicology testing market. Whereas, synergetic relationships between various stakeholders of the industry, and increasing toxicology databases to facilitate the use of in vitro test methods are expected to offer significant growth opportunities for the players operating in the market. Increasing focus of pharmaceutical and cosmetic industry on using in-vitro method for product testing along with improvement in silico methods for predictive toxicology studies will offer growth opportunity to the target market. However, failure to establish intricacies of in vivo conditions and limited in vitro models to test complex endpoints hinders the growth of this market. In addition, the dearth of skilled professionals is a substantial market challenge.

The in-vitro toxicology/toxicity testing market is segmented based on product and service, method, toxicity end point, technology, industry, and region.

Based on product and service, the in-vitro toxicology/toxicity testing market is segmented into consumables, assays, equipment, software, and services. The assays are further classified into bacterial toxicity assays, enzyme toxicity assays, cell-based elisa and western blots, receptor-binding assays, tissue culture assays, and other assays. Based on the method, the target market is segmented into cellular assays, biochemical assays, in silico models, and ex vivo models. Based on toxicity end point, the market is classified into ADME, skin irritation, corrosion and sensitization, genotoxicity testing, cytotoxicity testing, ocular toxicity, organ toxicity, phototoxicity testing, dermal toxicity, and other toxicity endpoints & tests. Based on technology, the target market is bifurcated into cell culture technologies, high-throughput technologies, toxicogenomics. On the basis of industry, the target market is segmented into pharmaceuticals and biopharmaceuticals, cosmetic and household products, food, and chemicals.

Regional Insights:

Based on the region the in-vitro toxicology/toxicity testing market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The market in Europe is expected to account significant revenue share to the market due to factors such as ban on animal testing for cosmetics and its ingredients. The market in Asia Pacific is estimated to grow at the highest CAGR during the forecast period. This is due to the emergence of CROs for outsourcing toxicology-related research projects, opposition animal testing resulting in the use of alternate methods, increasing pharmaceutical drug pipeline, and growing consumer awareness of product safety.

In-Vitro Toxicology/Toxicity Testing Market, By Product and service:

• Consumables
• Assays
  • Bacterial Toxicity Assays
  • Enzyme Toxicity Assays
  • Cell-based Elisa and Western Blots
  • Receptor-binding Assays
  • Tissue Culture Assays
  • Other Assays
• Equipment
• Software
• Services

In-Vitro Toxicology/Toxicity Testing Market, By Method:

• Cellular Assays
• Biochemical Assays
• In Silico Models
• Ex Vivo Models

In-Vitro Toxicology/Toxicity Testing Market, By Toxicity End Point

• ADME
• Skin Irritation
• Corrosion and Sensitization
• Genotoxicity Testing
• Cytotoxicity Testing
• Ocular Toxicity
• Organ Toxicity
• Phototoxicity Testing
• Dermal Toxicity
• Other Toxicity Endpoints & Tests

In-Vitro Toxicology/Toxicity Testing Market, By Technology:

• Cell Culture Technologies
• High-throughput Technologies
• Toxicogenomics

In-Vitro Toxicology/Toxicity Testing Market, By Industry:

• Pharmaceuticals and Biopharmaceutical
• Cosmetic and Household Products
• Food
• Chemicals

In-Vitro Toxicology/Toxicity Testing Market, By Region:

• North America
  • Middle East & Africa
    • Middle East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Product
    • Middle East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Method
    • Middle East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Toxicity End Point
    • Middle East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Technology
    • Middle-East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Industry
    • Middle East & Africa In-Vitro Toxicology/Toxicity Testing Market, By Country
      • GCC
      • Israel
      • South Africa
      • Rest of Middle East & Africa
  • Latin America
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Product and Service
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Method
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Toxicity End Point
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Technology
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Industry
    • Latin America In-Vitro Toxicology/Toxicity Testing Market, By Country
      • Brazil
      • Mexico
      • Rest of Latin America
  • Asia Pacific
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Product and Service
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Method
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Toxicity End Point
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Technology
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Industry
    • Asia Pacific In-Vitro Toxicology/Toxicity Testing Market, By Country
      • China
      • India
      • Japan
      • South Korea
      • Rest of Asia Pacific
  • Europe
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Product and Service
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Method
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Toxicity End Point
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Technology
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Industry
    • Europe In-Vitro Toxicology/Toxicity Testing Market, By Country
      • Germany
      • UK
      • France
      • Russia
      • Italy
      • Rest of Europe
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Product and Service
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Method
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Toxicity Endpoint
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Technology
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Industry
  • North America In-Vitro Toxicology/Toxicity Testing Market, By Country
    • U.S.
    • Canada

The key players operating the in-vitro toxicology/toxicity testing market involves Thermo Fisher Scientific, Covance, Bio-Rad Laboratories, GE Healthcare, Eurofins Scientific, Merck KgaA, Charles River Laboratories International, Catalent, Cyprotex, SGS S.A. 

• Thermo Fisher Scientific
  • Company Overview
  • Product Portfolio
  • Key Highlights
  • Financial Performance
• Covance
• Bio-Rad Laboratories
• GE Healthcare
• Eurofins Scientific
• Merck KgaA
• Charles River Laboratories International
• Catalent
• Cyprotex
• SGS S.A. 

 “*” marked represents similar segmentation in other categories in the respective section