Bone Graft Substitutes Market, By Type (Allograft (Machined Allograft and Demineralized Bone Matrix), Bone Graft Substitute (Bone Morphogenic Proteins (BMP) and Synthetic Bone Grafts), and Cell-based Matrices), By Application (Spinal Fusion, Trauma, Joint Reconstruction, Dental Bone Grafting, and Craniomaxillofacial), and By Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Trends, Analysis and Forecast till 2030

Report Code: PMI429820 | Publish Date: March 2024 | No. of Pages: 178

Global Bone Graft Substitutes Market Overview

Bone grafting is a surgical procedure which involves healing of broken bones i.e. fractures by replacement material. This surgical technique is been done to treat extremely complex bone defects and possess significant health risk to patients. The Bone Graft Substitutes Market accounted for US$ 2.78 billion in 2020 and is estimated to be 4.19 billion by 2030 and is anticipated to register a CAGR of 4.1%.

Global Bone Graft Substitutes Market Dynamics

Growing number of orthopedic surgeries

Bone grafts and substitutes are orthopedic surgeries extensively utilized in for various applications. Increasing cases of orthopedic problems caused due to weakened bones are expected to drive the demand for the target market. As per the data published by Department of Economic and Social Affairs, United Nations, Population Division, in 2013 the number of people aged above 60 was 841 million and is estimated to reach 2 billion in 2050. Hence, the number of orthopedic surgeries is projected to increasing with rising geriatric population prone to orthopedic ailments. Thus, the market is expected to register significant demand in the coming years.

Rising adoption of minimally invasive surgeries

Growing adoption of minimally invasive surgeries (MIS) is also rising the demand for bone graft substitutes market. Specialists are opting for MIS instead of open surgery due to associated benefits such as reduced post-operative duration, minimal pain, and less injury to the tissue. According to Minim Invasive Surg in 2018, around 400,000 spinal fusion cases are implemented in the U.S. per year and it ranks one of the most frequently performed and well-established treatment options for degenerative disorders, spine trauma, tumors, and structural abnormalities.

Conversely, ethical issues associated with bone grafting procedures and high cost of surgeries might hamper growth of the target market.

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Global Bone Graft Substitutes Market Segmentation

Bone graft substitutes market is segmented based on type, application, and region.

On the basis of type, the bone graft substitutes market is segmented into allograft (machined allograft and demineralized bone matrix), bone graft substitute (bone morphogenic proteins (BMP) and synthetic bone grafts), and cell-based matrices. On the basis of application, the target market is classified into spinal fusion, trauma, joint reconstruction, dental bone grafting, and craniomaxillofacial.

Regional Insights:

The bone graft substitutes market accounted for US$ 2.78 billion in 2020 and is estimated to be 4.19 billion by 2030 and is anticipated to register a CAGR of 4.1%.. On region the global bone graft substitutes market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America forecast highest revenue share in 2018, owing to higher healthcare expenditure, growing awareness regarding the commercially available products, and presence of advanced healthcare infrastructure. Asia Pacific region is projected to register lucrative growth in the coming years. The growth can be attributed due to favorable government initiatives and increased medical tourism. However, stringent guidelines hamper the adoption in some of the countries. In Australia, the products should be approved by Therapeutic Goods Administration (TGA). In case of South Korea, the product are regulated by the Korean Food and Drug Administration (KFDA) before marketing.

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Report Scope:

Attribute

Details

Base year for estimation

2018

Forecast period

2018 – 2026

Market representation

Revenue in USD Million & CAGR from 2018 – 2026

Market Segmentation

By Type - Allograft (Machined Allograft and Demineralized Bone Matrix), Bone Graft Substitute (Bone Morphogenic Proteins (BMP) and Synthetic Bone Grafts), and Cell-based Matrices

By Application - Spinal Fusion, Trauma, Joint Reconstruction, Dental Bone Grafting, and Craniomaxillofacial

Regional scope

North America - U.S., Canada

Europe - UK, Germany, Spain, France, Italy, Russia, Rest of Europe

Asia Pacific - Japan, India, China, South Korea, Australia, Rest of Asia-Pacific

Latin America - Brazil, Mexico, Argentina, Rest of Latin America

Middle East & Africa - South Africa, Saudi Arabia, UAE, Rest of Middle East & Africa

Report coverage

Revenue forecast, company share, competitive landscape, growth factors, and trends

Segments Covered in the Report:

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest application trends and opportunities in each of the sub-segments from 2019 to 2026. For the purpose of this study, has segmented the global bone graft substitute’s market report based on type, application, and region.

Bone Graft Substitutes Market, By Type:

  • Allograft
  • Machined Allograft
  • Demineralized Bone Matrix
  • Bone Graft Substitute
  • Bone Morphogenic Proteins (BMP)
  • Synthetic Bone Grafts
  • Cell-based Matrices

 Bone Graft Substitutes Market, By Application:

  • Spinal Fusion
  • Trauma
  • Joint Reconstruction
  • Dental Bone Grafting
  • Craniomaxillofacial

Bone Graft Substitutes Market, By Region:

  • North America
    • Middle East & Africa
        • GCC
        • Israel
        • South Africa
        • Rest of Middle East & Africa
    • Latin America
        • Brazil
        • Mexico
        • Rest of Latin America
    • Asia Pacific
        • China
        • India
        • Japan
        • South Korea
        • Rest of Asia Pacific
    • Europe
        • Germany
        • UK
        • France
        • Russia
        • Italy
        • Rest of Europe
      • U.S.
      • Canada

Global Bone Graft Substitutes Market Key Players

The key players operating the bone graft substitutes market includes Arthrex, Inc., Baxter International Inc., Johnson & Johnson (DePuy Synthes), Medtronic Plc., Integra LifeSciences Holdings Corporation, Musculoskeletal Transplant Foundation, Stryker Corporation, Wright Medical Group N.V., NuVasive, Inc., and Zimmer Biomet Holdings, Inc. Key players are undertaking policies such as collaborations, partnerships, mergers, and acquisitions to support their market position. Depuy Synthes, Medtronic, & Stryker account for the major revenue share of bone graft substitutes market. In July 2018, NuVasive, Inc. introduced AttraX scaffold bone graft, a ceramic-collagen bone graft to expand its product portfolio. In September 2019, Kuros BioSciences developed MagnetOs which is projected to enhance bone regeneration in spinal fusion and other orthopedic procedures.

Global Bone Graft Substitutes Market Company Profile

  • Arthrex, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Baxter International Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Johnson & Johnson (DePuy Synthes)
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Medtronic Plc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Integra LifeSciences Holdings Corporation
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Musculoskeletal Transplant Foundation
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Stryker Corporation
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Wright Medical Group N.V.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • NuVasive, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies
  • Zimmer Biomet Holdings, Inc.
    • Company Overview
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Business Strategies

Global Bone Graft Substitutes Market Table of Contents

  1. Research Objective and Assumption
    • Preface
    • Research Objectives
    • Study Scope
    • Years Considered for the study
    • Assumptions
    • Abbreviations
  2. Research Methodology
    • Research data
    • Primary Data
      • Primary Interviews
      • Primary Breakdown
      • Key data from Primary Sources
      • Key Thickness Insights
    • Secondary Data
      • Major Secondary Sources
      • Secondary Sources
    • Market Estimation
    • Top-Down Approach
      • Approach for estimating Market Share by Top-Down Analysis (Supply Side)
    • Bottom-Up Approach
      • Approach for estimating market share by Bottom-up Analysis (Demand Side)
    • Market Breakdown and Data Triangulation
    • Research Assumptions
  3. Market Purview
    • Executive Summary
    • Key Findings—Global Outlook for Bone Graft Substitutes Strategies
      • Key Questions this Study will Answer
      • Market Snippet, By Type
      • Market Snippet, By Application
      • Market Snippet, By Region
    • Opportunity Map Analysis
    • Executive Summary—3 Big Predictions
  4. Market Dynamics, Regulations, and Trends Analysis
    • Market Dynamics
      • Drivers
      • Restraints
      • Market Opportunities
      • Market Trends
    • DR Impact Analysis
    • PEST Analysis
    • Porter’s Five Forces Analysis
    • Opportunity Orbit
    • Market Investment Feasibility Index
    • Macroeconomic Factor Analysis
  5. Bone Graft Substitutes Market, By Type, 2020 – 2029, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2029
      • Y-o-Y Growth Analysis (%), 2020 – 2029
      • Segment Trends
    • Allograft
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
        • Machined Allograft
        • Demineralized Bone Matrix
    • Bone Graft Substitute
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
        • Bone Morphogenic Proteins (BMP)
        • Synthetic Bone Grafts
    • Cell-based Matrices
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
  6. Bone Graft Substitutes Market, By Application, 2020 – 2029, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2029
      • Y-o-Y Growth Analysis (%), 2020 – 2029
      • Segment Trends
    • Spinal Fusion
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
    • Trauma
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
    • Joint Reconstruction
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
    • Dental Bone Grafting
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
    • Craniomaxillofacial
      • Overview
      • Market Size and Forecast (US$ Mn), and Y-o-Y Growth (%), 2020 – 2029
  7. Bone Graft Substitutes Market, By Region, 2020 – 2029, (US$ Mn)
    • Overview
      • Market Value and Forecast (US$ Mn), and Share Analysis (%), 2020 – 2029
      • Y-o-Y Growth Analysis (%), 2020 – 2029
      • Regional Trends
    • North America
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2029
        • U.S.
        • Canada
    • Europe
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2029
        • Germany
        • UK
        • France
        • Russia
        • Italy
        • Rest of Europe
    • Asia Pacific
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2029
        • China
        • India
        • Japan
        • South Korea
        • Rest of Asia Pacific
    • Latin America
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2029
      • Market Size  and Forecast (US$ Mn), By Country, 2020 – 2029
        • Brazil
        • Mexico
        • Rest of Latin America
    • Middle East & Africa
      • Market Size and Forecast (US$ Mn), By Type, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Application, 2020 – 2029
      • Market Size and Forecast (US$ Mn), By Country, 2020 – 2029
        • GCC
        • Israel
        • South Africa
        • Rest of Middle East
  8. Competitive Landscape
    • Heat Map Analysis
    • Market Presence and Specificity Analysis
  9. Company Profiles
      • Arthrex, Inc.
        • Company Overview
        • Type Portfolio
        • Key Highlights
        • Financial Overview
        • Business Strategies
      • Baxter International Inc.
      • Johnson & Johnson (DePuy Synthes)
      • Medtronic Plc.
      • Integra LifeSciences Holdings Corporation
      • Musculoskeletal Transplant Foundation
      • Stryker Corporation
      • Wright Medical Group N.V.
      • NuVasive, Inc.
      • Zimmer Biomet Holdings, Inc.
  10. The Last Word
    • Future Impact
    • About Us
    • Contact

FAQs

The global bone graft substitutes market is segmented based on type, application, and region.

Bone grafts and substitutes are orthopedic surgeries extensively utilized in for various applications. Increasing cases of orthopedic problems caused due to weakened bones are expected to drive the demand for the target market.

North America forecast highest revenue share in 2018, owing to higher healthcare expenditure, growing awareness regarding the commercially available products, and presence of advanced healthcare infrastructure.

The key players operating the global bone graft substitutes market includes Arthrex, Inc., Baxter International Inc., Johnson & Johnson (DePuy Synthes), Medtronic Plc., Integra LifeSciences Holdings Corporation, Musculoskeletal Transplant Foundation, Stryker Corporation, Wright Medical Group N.V., NuVasive, Inc., and Zimmer Biomet Holdings, Inc.